Dataset | set04_transDMproB_versus_DMpreB |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_pos |
GeneSet | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY |
Enrichment Score (ES) | 0.5187359 |
Normalized Enrichment Score (NES) | 1.8476533 |
Nominal p-value | 0.0 |
FDR q-value | 0.049671777 |
FWER p-Value | 0.361 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | STAT4 | 7 | 37.571 | 0.0618 | Yes | ||
2 | KIT | 44 | 22.388 | 0.0969 | Yes | ||
3 | PRKCH | 92 | 18.399 | 0.1248 | Yes | ||
4 | JAK3 | 108 | 17.689 | 0.1533 | Yes | ||
5 | GFRA1 | 177 | 14.371 | 0.1734 | Yes | ||
6 | PRKCQ | 196 | 14.046 | 0.1956 | Yes | ||
7 | MAPKAPK2 | 276 | 12.560 | 0.2121 | Yes | ||
8 | STAT1 | 359 | 11.544 | 0.2268 | Yes | ||
9 | MAP3K11 | 373 | 11.326 | 0.2449 | Yes | ||
10 | JAK2 | 399 | 10.951 | 0.2616 | Yes | ||
11 | MAP3K3 | 488 | 10.054 | 0.2735 | Yes | ||
12 | STAT3 | 490 | 10.026 | 0.2900 | Yes | ||
13 | FYN | 553 | 9.371 | 0.3022 | Yes | ||
14 | MAPK9 | 558 | 9.321 | 0.3174 | Yes | ||
15 | MAP4K2 | 708 | 8.299 | 0.3231 | Yes | ||
16 | MAPK14 | 754 | 8.054 | 0.3340 | Yes | ||
17 | STAT5A | 807 | 7.710 | 0.3439 | Yes | ||
18 | TGFBR1 | 893 | 7.218 | 0.3513 | Yes | ||
19 | MAP3K5 | 939 | 7.023 | 0.3605 | Yes | ||
20 | IKBKG | 992 | 6.767 | 0.3688 | Yes | ||
21 | PAK4 | 998 | 6.757 | 0.3797 | Yes | ||
22 | PDPK1 | 1005 | 6.715 | 0.3905 | Yes | ||
23 | ZAP70 | 1027 | 6.606 | 0.4003 | Yes | ||
24 | ACVR1 | 1096 | 6.352 | 0.4072 | Yes | ||
25 | MAP3K14 | 1121 | 6.262 | 0.4162 | Yes | ||
26 | MAP4K3 | 1137 | 6.199 | 0.4257 | Yes | ||
27 | RPS6KA2 | 1164 | 6.074 | 0.4343 | Yes | ||
28 | LCK | 1176 | 6.008 | 0.4437 | Yes | ||
29 | RIPK1 | 1256 | 5.685 | 0.4488 | Yes | ||
30 | PRKCD | 1279 | 5.615 | 0.4569 | Yes | ||
31 | STAT2 | 1309 | 5.493 | 0.4644 | Yes | ||
32 | BTK | 1419 | 5.180 | 0.4671 | Yes | ||
33 | MKNK2 | 1428 | 5.146 | 0.4752 | Yes | ||
34 | TYK2 | 1545 | 4.831 | 0.4769 | Yes | ||
35 | CAMK2G | 1609 | 4.673 | 0.4812 | Yes | ||
36 | PTK2B | 1651 | 4.557 | 0.4866 | Yes | ||
37 | MAPK3 | 1689 | 4.468 | 0.4919 | Yes | ||
38 | PAK1 | 1819 | 4.193 | 0.4919 | Yes | ||
39 | IGF1R | 1820 | 4.193 | 0.4988 | Yes | ||
40 | AKT3 | 1834 | 4.165 | 0.5050 | Yes | ||
41 | TEC | 1903 | 4.018 | 0.5080 | Yes | ||
42 | PDGFRB | 2130 | 3.579 | 0.5017 | Yes | ||
43 | CDK5 | 2136 | 3.562 | 0.5073 | Yes | ||
44 | GSK3B | 2190 | 3.495 | 0.5102 | Yes | ||
45 | JAK1 | 2268 | 3.366 | 0.5116 | Yes | ||
46 | IKBKE | 2365 | 3.191 | 0.5117 | Yes | ||
47 | MAP2K3 | 2462 | 3.060 | 0.5116 | Yes | ||
48 | CDK6 | 2494 | 3.022 | 0.5149 | Yes | ||
49 | MAP3K12 | 2516 | 2.987 | 0.5187 | Yes | ||
50 | ALK | 2866 | 2.538 | 0.5041 | No | ||
51 | MAP3K1 | 2926 | 2.475 | 0.5050 | No | ||
52 | ACVR2A | 3262 | 2.133 | 0.4904 | No | ||
53 | FGFR1 | 3267 | 2.130 | 0.4937 | No | ||
54 | CSK | 3411 | 2.002 | 0.4893 | No | ||
55 | RPS6KA1 | 3662 | 1.805 | 0.4787 | No | ||
56 | MAPK13 | 3729 | 1.763 | 0.4781 | No | ||
57 | CAMK2A | 3986 | 1.586 | 0.4668 | No | ||
58 | CAMK2B | 4013 | 1.572 | 0.4680 | No | ||
59 | MAP3K8 | 4079 | 1.535 | 0.4671 | No | ||
60 | MAP3K7 | 4650 | 1.199 | 0.4382 | No | ||
61 | PRKG1 | 4918 | 1.078 | 0.4255 | No | ||
62 | MAP2K1 | 5069 | 1.006 | 0.4191 | No | ||
63 | PLK1 | 5303 | 0.896 | 0.4080 | No | ||
64 | ACVRL1 | 5363 | 0.872 | 0.4062 | No | ||
65 | BMPR1B | 5701 | 0.730 | 0.3892 | No | ||
66 | RAF1 | 5794 | 0.702 | 0.3854 | No | ||
67 | ARAF | 6377 | 0.479 | 0.3547 | No | ||
68 | LTK | 7099 | 0.234 | 0.3161 | No | ||
69 | ACVR2B | 7178 | 0.210 | 0.3122 | No | ||
70 | NLK | 7210 | 0.198 | 0.3109 | No | ||
71 | MAP3K2 | 7250 | 0.182 | 0.3090 | No | ||
72 | ITK | 8160 | -0.091 | 0.2600 | No | ||
73 | PAK3 | 8212 | -0.104 | 0.2574 | No | ||
74 | PRKCI | 8291 | -0.129 | 0.2534 | No | ||
75 | PRKCA | 8501 | -0.195 | 0.2424 | No | ||
76 | STAT5B | 8605 | -0.224 | 0.2372 | No | ||
77 | NGFR | 9360 | -0.448 | 0.1972 | No | ||
78 | MOS | 9978 | -0.620 | 0.1648 | No | ||
79 | KDR | 10022 | -0.636 | 0.1636 | No | ||
80 | FGFR3 | 10044 | -0.643 | 0.1635 | No | ||
81 | RPS6KB2 | 10135 | -0.665 | 0.1597 | No | ||
82 | BMPR2 | 10269 | -0.699 | 0.1537 | No | ||
83 | PRKACA | 10529 | -0.773 | 0.1410 | No | ||
84 | PRKAR1B | 10560 | -0.783 | 0.1406 | No | ||
85 | MNAT1 | 10657 | -0.812 | 0.1368 | No | ||
86 | PRKCZ | 10666 | -0.815 | 0.1377 | No | ||
87 | MAP2K6 | 10855 | -0.863 | 0.1290 | No | ||
88 | MET | 10966 | -0.894 | 0.1245 | No | ||
89 | MAPKAPK5 | 11101 | -0.933 | 0.1188 | No | ||
90 | WEE1 | 11125 | -0.938 | 0.1191 | No | ||
91 | EGFR | 11555 | -1.062 | 0.0976 | No | ||
92 | PRKCE | 11664 | -1.095 | 0.0936 | No | ||
93 | FLT4 | 12043 | -1.210 | 0.0752 | No | ||
94 | FGFR4 | 12077 | -1.220 | 0.0754 | No | ||
95 | SRC | 12150 | -1.245 | 0.0736 | No | ||
96 | PDGFRA | 12296 | -1.285 | 0.0678 | No | ||
97 | MAP2K4 | 12313 | -1.290 | 0.0691 | No | ||
98 | RPS6KA3 | 12621 | -1.384 | 0.0548 | No | ||
99 | TGFBR2 | 12638 | -1.390 | 0.0562 | No | ||
100 | SYK | 12848 | -1.460 | 0.0473 | No | ||
101 | MKNK1 | 13042 | -1.520 | 0.0394 | No | ||
102 | MAPK11 | 13069 | -1.528 | 0.0405 | No | ||
103 | MAPK7 | 13332 | -1.628 | 0.0291 | No | ||
104 | PRKG2 | 13466 | -1.679 | 0.0246 | No | ||
105 | AKT1 | 13635 | -1.741 | 0.0184 | No | ||
106 | BMPR1A | 13669 | -1.753 | 0.0195 | No | ||
107 | FLT1 | 13723 | -1.780 | 0.0196 | No | ||
108 | CDK7 | 13862 | -1.838 | 0.0152 | No | ||
109 | INSR | 13875 | -1.845 | 0.0176 | No | ||
110 | MAPK10 | 14173 | -1.978 | 0.0048 | No | ||
111 | RIPK3 | 14411 | -2.097 | -0.0045 | No | ||
112 | IRAK4 | 14544 | -2.169 | -0.0081 | No | ||
113 | IRAK1 | 14586 | -2.187 | -0.0067 | No | ||
114 | MAP2K2 | 14962 | -2.404 | -0.0230 | No | ||
115 | PAK2 | 15078 | -2.476 | -0.0251 | No | ||
116 | IKBKB | 15115 | -2.507 | -0.0229 | No | ||
117 | FGFR2 | 15223 | -2.586 | -0.0244 | No | ||
118 | GRK6 | 15616 | -2.892 | -0.0409 | No | ||
119 | MAPK8 | 15721 | -2.984 | -0.0415 | No | ||
120 | AKT2 | 16062 | -3.372 | -0.0544 | No | ||
121 | PLK3 | 16066 | -3.375 | -0.0489 | No | ||
122 | CDK2 | 16319 | -3.710 | -0.0564 | No | ||
123 | RIPK2 | 16429 | -3.880 | -0.0559 | No | ||
124 | CCNH | 16501 | -4.006 | -0.0531 | No | ||
125 | CHUK | 16867 | -4.706 | -0.0651 | No | ||
126 | PRKAR2B | 16973 | -4.887 | -0.0627 | No | ||
127 | MAPK12 | 17181 | -5.426 | -0.0649 | No | ||
128 | CSNK1E | 17216 | -5.524 | -0.0576 | No | ||
129 | PRKAR2A | 17556 | -6.541 | -0.0651 | No | ||
130 | CDK4 | 18013 | -8.589 | -0.0755 | No | ||
131 | PTK2 | 18609 | -26.874 | -0.0633 | No | ||
132 | RYK | 18613 | -38.424 | 0.0002 | No |